Carmoterol hydrochloride

Modify Date: 2024-01-09 19:10:49

Carmoterol hydrochloride Structure
Carmoterol hydrochloride structure
Common Name Carmoterol hydrochloride
CAS Number 137888-11-0 Molecular Weight 404.887
Density N/A Boiling Point 649.1ºC at 760mmHg
Molecular Formula C21H25ClN2O4 Melting Point N/A
MSDS N/A Flash Point 346.4ºC

 Use of Carmoterol hydrochloride


Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD)[1][2].

 Names

Name Carmoterol Hydrochloride
Synonym More Synonyms

 Carmoterol hydrochloride Biological Activity

Description Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD)[1][2].
Related Catalog
References

[1]. Mario Cazzola, et al. β(2) -adrenoceptor agonists: current and future direction. Br J Pharmacol. 2011 May;163(1):4-17.  

[2]. Giuseppe Rossoni, et al. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. Pulm Pharmacol Ther. 2007;20(3):250-7.  

 Chemical & Physical Properties

Boiling Point 649.1ºC at 760mmHg
Molecular Formula C21H25ClN2O4
Molecular Weight 404.887
Flash Point 346.4ºC
Exact Mass 404.150299
PSA 94.58000
LogP 3.68940

 Synonyms

8-Hydroxy-5-((1R)-1-hydroxy-2-(N-(1R)-2-(p-methoxyphenyl)isopropylamino)ethyl)carbostyril HCl
8-Hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)-2-propanyl]amino}ethyl]-2(1H)-quinolinone hydrochloride (1:1)
Carmoterol hydrochloride
8-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]-1,2-dihydroquinolin-2-one hydrochloride
2(1H)-Quinolinone, 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-, hydrochloride (1:1)
8-Hydroxy-5-(1-hydroxy-2-(N-(2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)carbostyril hydrochloride