(S)-FQI1

Modify Date: 2024-04-09 19:35:29

(S)-FQI1 Structure
(S)-FQI1 structure
Common Name (S)-FQI1
CAS Number 1373209-39-2 Molecular Weight 311.33
Density N/A Boiling Point N/A
Molecular Formula C18H17NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-FQI1


(S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1; inhibits LSF DNA-binding activity both in vitro, also exhibits antiproliferative activity in multiple cell lines, NIH 3T3, HeLa S3, and A549 cells with GI50 of 0.82, 0.30, and 1.2 uM, respectively; rapidly induces cell death in QGY-7703 liver cancer cell lines.

 Names

Name (S)-FQI1

 (S)-FQI1 Biological Activity

Description (S)-FQI1 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.93 uM, approximately 2-fold more active than the racemate FQI-1; inhibits LSF DNA-binding activity both in vitro, also exhibits antiproliferative activity in multiple cell lines, NIH 3T3, HeLa S3, and A549 cells with GI50 of 0.82, 0.30, and 1.2 uM, respectively; rapidly induces cell death in QGY-7703 liver cancer cell lines.
References References 1. Grant TJ, et al. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4503-8. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C18H17NO4
Molecular Weight 311.33
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