CM-118

Modify Date: 2024-03-17 18:25:51

CM-118 Structure
CM-118 structure
Common Name CM-118
CAS Number 1370652-56-4 Molecular Weight 452.27
Density N/A Boiling Point N/A
Molecular Formula C19H16Cl2FN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CM-118


CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells.

 Names

Name CM-118

 CM-118 Biological Activity

Description CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells.

 Chemical & Physical Properties

Molecular Formula C19H16Cl2FN5O3
Molecular Weight 452.27
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