CM-118

Names

[ Name ]:
CM-118

Biological Activity

[Description]:

CM-118 is a potent and selective dual inhibitor of c-Met and ALK which potently abrogates hepatocyte growth factor (HGF)-induced c-Met phosphorylation and cell migration, as well as phosphorylation of ALK, EML4-ALK, and ALK resistance mutants in transfected cells.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆Cl₂FN₅O₃

[ Molecular Weight ]:
452.27