Lubiprostone
Modify Date: 2024-01-02 18:12:45
Lubiprostone structure
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Common Name | Lubiprostone | ||
|---|---|---|---|---|
| CAS Number | 136790-76-6 | Molecular Weight | 390.462 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 532.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H32F2O5 | Melting Point | 56-59ºC | |
| MSDS | Chinese USA | Flash Point | 275.7±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of LubiprostoneLubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia. |
| Name | Lubiprostone |
|---|---|
| Synonym | More Synonyms |
| Description | Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 532.3±50.0 °C at 760 mmHg |
| Melting Point | 56-59ºC |
| Molecular Formula | C20H32F2O5 |
| Molecular Weight | 390.462 |
| Flash Point | 275.7±30.1 °C |
| Exact Mass | 390.221771 |
| PSA | 83.83000 |
| LogP | 2.85 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.486 |
| Storage condition | -20°C Freezer |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| RTECS | UK8257750 |
| HS Code | 2918990090 |
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Lubiprostone CAS#:136790-76-6 |
| Literature: APOTEX PHARMACHEM INC.; KOTHAKONDA, Kiran, Kumar; WANG, Fan; GUNTOORI, Bhaskar, Reddy; NGUYEN, Minh, T.N.; CECCARELLI, Alfredo, Paul; ZHAO, Yajun; KOTIPALLI, Uma; DUNCAN, Sammy, Chris; MILNEE, Kaarina, K.; KELLS, Kevin, W.; MONTEMAYOR, Laura, Kaye Patent: WO2010/83597 A1, 2010 ; Location in patent: Page/Page column 54-55 ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; Page/Page column 13-14 ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
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Lubiprostone CAS#:136790-76-6 |
| Literature: WO2011/91513 A1, ; |
![benzyl (Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoate structure](https://www.chemsrc.com/caspic/028/1236109-40-2.png)
![(Z)-7-[(1R,2R,3R)-2-((E)-4,4-difluoro-3-oxo-1-octenyl)-3-(phenylmethoxy)-5-oxocyclopentyl]-5-heptenoic acid structure](https://www.chemsrc.com/caspic/100/1236109-29-7.png)
![[(3aR,4R,5R,6aS)-hexahydro-2-oxo-5-(phenylmethoxy)-2H-cyclopenta[b]furan-4-carboxaldehyde] structure](https://www.chemsrc.com/caspic/056/163074-98-4.png)
![[(3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4(triisopropylsilyloxymethyl)-2H-cyclopenta[b]furan-2-one] structure](https://www.chemsrc.com/caspic/290/1236109-24-2.png)
![[(3aR,4S,5R,6aS)-hexahydro-4-(triisopropylsilyloxymethyl)-5-(phenylmethoxy)-2H-cyclopenta[b]furan-2-one] structure](https://www.chemsrc.com/caspic/252/1236109-25-3.png)
![[3Ar-(3aalpha,4alpha,5beta,6aalpha)]-hexahydro-4-(hydroxymethyl)-5-(phenylmethoxy)-2H-cyclopenta[b]furan-2-one structure](https://www.chemsrc.com/caspic/108/81190-06-9.png)
CAS#:333963-40-9| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11α,15R)- |
| 13,14-dihydro-15-keto-16,16-difluoro-Prostaglandin E1 |
| 9ALPHA-HYDROXY-11,15-DIOXO-PROST-5Z-EN-1-OIC ACID |
| 13,14-dihydro-15-keto Prostaglandin D2 Lipid Maps MS Standard |
| DK-PGD2 |
| (3aR,4R,5R,6aS)-4-[(1E)-4,4-Difluoro-3-oxo-1-octen-1-yl]-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl 4-biphenylcarboxylate |
| 13,14-dihydro-15-keto-prostaglandin D2 |
| [1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-4-[(1E)-4,4-difluoro-3-oxo-1-octen-1-yl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester |
| 13,14-Dihydro-15-keto-PGD2 |
| 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic acid |
| 13,14-Dihydro-15-ketoprostadlandin D2 |
| Lubiprostone |
| (11α,15R)-16,16-Difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid |
| 13,14-dihydro-15-keto PD2 |
| 13,14-dihydro-15-keto-16,16-difluoro-PGE1 |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Lubiprostone
- Price: ￥1058.0/5mg ￥1128.0/10mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Lubiprostone
- Price: $700.0/100mg $1200.0/250mg $2500.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Lubiprostone
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Lubiprostone
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: TIANFU-CHEM - Lubiprostone
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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Price: $72/10mM*1mLinDMSO
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