Quinalphos

Modify Date: 2025-08-25 20:52:47

Quinalphos structure	Common Name	Quinalphos
	CAS Number	13593-03-8	Molecular Weight	298.298
	Density	1.3±0.1 g/cm3	Boiling Point	387.0±45.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₅N₂O₃PS	Melting Point	31-32ºC
	MSDS	Chinese USA	Flash Point	187.9±28.7 °C
	Symbol	GHS05, GHS06, GHS09	Signal Word	Danger

Name	quinalphos
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	387.0±45.0 °C at 760 mmHg
Melting Point	31-32ºC
Molecular Formula	C₁₂H₁₅N₂O₃PS
Molecular Weight	298.298
Flash Point	187.9±28.7 °C
Exact Mass	298.054108
PSA	95.37000
LogP	3.53
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.604

Quinalphos MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TF6125000

CHEMICAL NAME :: Phosphorothioic acid, O,O-diethyl O-(2-quinoxalinyl) ester

CAS REGISTRY NUMBER :: 13593-03-8

BEILSTEIN REFERENCE NO. :: 0754823

LAST UPDATED :: 199710

DATA ITEMS CITED :: 34

MOLECULAR FORMULA :: C12-H15-N2-O3-P-S

MOLECULAR WEIGHT :: 298.32

WISWESSER LINE NOTATION :: T66 BN ENJ COPS&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 26 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 175 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 39 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 74500 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - muscle contraction or spasticity Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 330 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - muscle contraction or spasticity Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - muscle contraction or spasticity Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - muscle contraction or spasticity Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 600 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 10500 ug/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 10250 ug/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - gerbil

DOSE/DURATION :: 11910 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - bronchiolar constriction Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 8500 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10800 mg/kg/90D-C

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 557 mg/kg/60D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 60 mg/kg/30D-C

TOXIC EFFECTS :: Brain and Coverings - changes in brain weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - changes in ovarian weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 22500 ug/kg

SEX/DURATION :: female 6-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7500 ug/kg

SEX/DURATION :: female 6-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 6500 ug/kg

SEX/DURATION :: male 26 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands Reproductive - Paternal Effects - other effects on male

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 6500 ug/kg

SEX/DURATION :: male 26 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - other effects on male Endocrine - changes in luteinizing hormone Endocrine - androgenic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 15 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 5 mg/kg

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 29,115,1991

Symbol	GHS05, GHS06, GHS09
Signal Word	Danger
Hazard Statements	H300 + H330-H311-H318-H410
Precautionary Statements	Missing Phrase - N15.00950417-P280-P302 + P352 + P312-P304 + P340 + P310-P305 + P351 + P338 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T: Toxic;N: Dangerous for the environment;Xn: Harmful;F: Flammable;
Risk Phrases	R21
Safety Phrases	S22-S36/37-S45-S60-S61-S26
RIDADR	2783
RTECS	TF6125000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2933990011

sodium quinoxal...

CAS#:57381-25-6

Diethyl chlorot...

CAS#:2524-04-1

~95%

Quinalphos

CAS#:13593-03-8

Literature: Ge, Xin; Qian, Chao; Chen, Xinzhi Phosphorus, Sulfur and Silicon and the Related Elements, 2013 , vol. 188, # 6 p. 739 - 744

Diethyl chlorot...

CAS#:2524-04-1

2(1H)-Quinoxalinone

CAS#:1196-57-2

~66%

Quinalphos

CAS#:13593-03-8

Literature: Ramadas; Janarthanan; Meera Rani Organic Preparations and Procedures International, 1998 , vol. 30, # 4 p. 469 - 472

Precursor 3
CAS#:57381-25-6 sodium quinoxal... CAS#:2524-04-1 Diethyl chlorot... CAS#:1196-57-2 2(1H)-Quinoxalinone
DownStream 0

HS Code	2933990011
Summary	2933990011 o,o-diethyl o-quinoxalin-2-yl phosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Fast agitated directly suspended droplet microextraction technique for the rapid analysis of eighteen organophosphorus pesticides in human blood.

J. Chromatogr. A. 1377 , 27-34, (2015)

A new sample preparation technique named as fast agitated directly suspended droplet microextraction (FA-DSDME) was proposed as an improved version of directly suspended droplet microextraction (DSDME...

Variation in effects of four OP insecticides on photosynthetic pigment fluorescence of Chlorella vulgaris Beij.

Ecotoxicol. Environ. Saf. 80 , 111-7, (2012)

Effects of the insecticides quinalphos, chlorfenvinphos, dimethoate and phorate on photosystem activity of Chlorella vulgaris were investigated by different chlorophyll fluorescence measurements. Expo...

Performance of clinical scoring systems in acute organophosphate poisoning.

Clin. Toxicol. (Phila.) 51(9) , 850-4, (2013)

Clinical scoring systems are used to predict mortality rate in hospitalized patients. Their utility in organophosphate (OP) poisoning has not been well studied.In this retrospective study of 396 patie...

Guinalphos

diethylquinalphione

MFCD00078719

EINECS 237-031-6

O,O-Diethyl O-(2-quinoxalinyl) thiophosphate

Quinalphos

Diethquinalphion

O,O-Diethyl O-2-quinoxalinyl phosphorothioate

O,O-Diethyl O-(quinoxalin-2-yl) thiophosphate

diethoxy-quinoxalin-2-yloxy-sulfanylidene-λ<sup>5</sup>-phosphane

O,O-Diethyl O-quinoxalin-2-yl phosphorothioate

chinalphos

Phosphorothioic acid, O,O-diethyl O-2-quinoxalinyl ester

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China
Product Name: Quinalphos
Price: ￥Inquiry/1g
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Quinalphos 13593-03-8
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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