HG-14-10-04

Modify Date: 2024-01-02 10:57:59

HG-14-10-04 Structure
HG-14-10-04 structure
Common Name HG-14-10-04
CAS Number 1356962-34-9 Molecular Weight 532.08000
Density N/A Boiling Point N/A
Molecular Formula C29H34ClN7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HG-14-10-04


HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.

 Names

Name 5-Chloro-4-(1H-indol-3-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidin-2-amine
Synonym More Synonyms

 HG-14-10-04 Biological Activity

Description HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.
Related Catalog
References

[1]. U.S. Pat. Appl. Publ. (2012), US 20120028924 A1

 Chemical & Physical Properties

Molecular Formula C29H34ClN7O
Molecular Weight 532.08000
Exact Mass 531.25100
PSA 72.55000
LogP 5.26050
Storage condition 2-8℃

 Synonyms

HG-14-10-04
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