Lobaplatin

Modify Date: 2024-01-06 11:33:11

Lobaplatin Structure
Lobaplatin structure
Common Name Lobaplatin
CAS Number 135558-11-1 Molecular Weight 395.31300
Density N/A Boiling Point 179.5ºC at 760 mmHg
Molecular Formula C9H16N2O3Pt Melting Point 220ºC
MSDS N/A Flash Point 75.1ºC

 Use of Lobaplatin


Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].

 Names

Name Platinum, [rel-(1R,2R)-1,2-cyclobutanedimethanamine-.kappa.N,.kappa.N'][(2S)-2-(hydroxy-.kappa.O)propanoato(2-)-.kappa.O]-, (SP-4-3)- (9CI) (CA INDEX NAME)

 Lobaplatin Biological Activity

Description Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].
Related Catalog
References

[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981.

[2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.

 Chemical & Physical Properties

Boiling Point 179.5ºC at 760 mmHg
Melting Point 220ºC
Molecular Formula C9H16N2O3Pt
Molecular Weight 395.31300
Flash Point 75.1ºC
Exact Mass 395.08100
PSA 75.27000
LogP 0.53800
Vapour Pressure 0.937mmHg at 25°C
Storage condition 2-8°C
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