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Lobaplatin

Names

[ CAS No. ]:
135558-11-1

[ Name ]:
Lobaplatin

Biological Activity

[Description]:

Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981.

[2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.

Chemical & Physical Properties

[ Boiling Point ]:
179.5ºC at 760 mmHg

[ Melting Point ]:
220ºC

[ Molecular Formula ]:
C9H16N2O3Pt

[ Molecular Weight ]:
395.31300

[ Flash Point ]:
75.1ºC

[ Exact Mass ]:
395.08100

[ PSA ]:
75.27000

[ LogP ]:
0.53800

[ Vapour Pressure ]:
0.937mmHg at 25°C

[ Storage condition ]:
2-8°C

Related Compounds