DC44SMe
Modify Date: 2024-04-09 19:49:19
DC44SMe structure
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Common Name | DC44SMe | ||
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| CAS Number | 1354787-76-0 | Molecular Weight | 806.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H37ClN5O7PS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DC44SMeDC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1]. |
| Name | DC44SMe |
|---|
| Description | DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1]. |
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| Related Catalog | |
| In Vitro | The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability[1]. |
| References |
| Molecular Formula | C38H37ClN5O7PS2 |
|---|---|
| Molecular Weight | 806.29 |