1354787-76-0
1354787-76-0 structure
- Name: DC44SMe
- Chemical Name: DC44SMe
- CAS Number: 1354787-76-0
- Molecular Formula: C38H37ClN5O7PS2
- Molecular Weight: 806.29
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
- Create Date: 2020-01-23 19:29:51
- Modify Date: 2024-04-09 19:49:19
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DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1].
| Name | DC44SMe |
|---|
| Description | DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1]. |
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| Related Catalog | |
| In Vitro | The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability[1]. |
| References |
| Molecular Formula | C38H37ClN5O7PS2 |
|---|---|
| Molecular Weight | 806.29 |