GWJ-A-23
Modify Date: 2025-08-25 09:16:21
GWJ-A-23 structure
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Common Name | GWJ-A-23 | ||
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| CAS Number | 1351930-95-4 | Molecular Weight | 385.346 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H28NO4P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GWJ-A-23GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo. |
| Name | Disodium [4-(decanoylamino)benzyl]phosphonate |
|---|---|
| Synonym | More Synonyms |
| Description | GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo. |
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| References | References 1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101. View Related Products by Target Autotaxin |
| Molecular Formula | C17H28NO4P |
|---|---|
| Molecular Weight | 385.346 |
| Exact Mass | 385.139496 |
| InChIKey | MCTIGBRKGWRZIZ-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCC(=O)Nc1ccc(CP(=O)(O)O)cc1 |
| Phosphonic acid, [[4-[(1-oxodecyl)amino]phenyl]methyl]-, sodium salt (1:2) |
| Disodium [4-(decanoylamino)benzyl]phosphonate |