1351930-95-4
1351930-95-4 structure
- Name: GWJ-A-23
- Chemical Name: Disodium [4-(decanoylamino)benzyl]phosphonate
- CAS Number: 1351930-95-4
- Molecular Formula: C17H28NO4P
- Molecular Weight: 385.346
- Create Date: 2020-01-11 12:24:02
- Modify Date: 2024-02-22 09:33:30
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GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo.
| Name | Disodium [4-(decanoylamino)benzyl]phosphonate |
|---|---|
| Synonyms |
Phosphonic acid, [[4-[(1-oxodecyl)amino]phenyl]methyl]-, sodium salt (1:2)
Disodium [4-(decanoylamino)benzyl]phosphonate |
| Description | GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo. |
|---|---|
| References | References 1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101. View Related Products by Target Autotaxin |
| Molecular Formula | C17H28NO4P |
|---|---|
| Molecular Weight | 385.346 |
| Exact Mass | 385.139496 |