Pegylated synthetic human c-peptide

Modify Date: 2024-01-03 14:08:54

Pegylated synthetic human c-peptide Structure
Pegylated synthetic human c-peptide structure
Common Name Pegylated synthetic human c-peptide
CAS Number 1350661-05-0 Molecular Weight 3018.52
Density N/A Boiling Point N/A
Molecular Formula C129H211N35O48 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pegylated synthetic human c-peptide


Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].

 Names

Name Pegylated synthetic human c-peptide

 Pegylated synthetic human c-peptide Biological Activity

Description Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].
Related Catalog
In Vivo Pegylated synthetic human c-peptide (CBX129801) (s.c., 0.4, 1.33 or 4.0 mg/kg/wk, 39 weeks) 可以导致给药后注射部位组织中空泡化巨噬细胞的细胞质浸润和引流腋窝淋巴结,而不会导致全身巨噬细胞空泡化[1]。
References

[1]. Dennis Naas, et al. A 9-Month Toxicity and Toxicokinetic Assessment of Subcutaneous Pegylated Human C-peptide (CBX129801) in Cynomolgus Monkeys. Int J Toxicol. 2015 Jul-Aug;34(4):318-24.   

 Chemical & Physical Properties

Molecular Formula C129H211N35O48
Molecular Weight 3018.52
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