1350661-05-0

1350661-05-0 structure

Name: Pegylated synthetic human c-peptide
Chemical Name: Pegylated synthetic human c-peptide
CAS Number: 1350661-05-0
Molecular Formula: C₁₂₉H₂₁₁N₃₅O₄₈
Molecular Weight: 3018.52
Catalog: Research Areas Metabolic Disease
Create Date: 2023-01-30 12:21:09
Modify Date: 2025-08-26 17:04:17
Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].

Name	Pegylated synthetic human c-peptide

Description	Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Pegylated synthetic human c-peptide (CBX129801) (s.c., 0.4, 1.33 or 4.0 mg/kg/wk, 39 weeks) 可以导致给药后注射部位组织中空泡化巨噬细胞的细胞质浸润和引流腋窝淋巴结，而不会导致全身巨噬细胞空泡化[1]。
References	[1]. Dennis Naas, et al. A 9-Month Toxicity and Toxicokinetic Assessment of Subcutaneous Pegylated Human C-peptide (CBX129801) in Cynomolgus Monkeys. Int J Toxicol. 2015 Jul-Aug;34(4):318-24.

Molecular Formula	C₁₂₉H₂₁₁N₃₅O₄₈
Molecular Weight	3018.52