Phthalamide-PEG3-azide

Modify Date: 2023-01-15 18:40:46

Phthalamide-PEG3-azide structure	Common Name	Phthalamide-PEG3-azide
	CAS Number	134179-44-5	Molecular Weight	348.35400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₀N₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Phthalamide-PEG3-azide

Phthalamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-azido-11-phthalimido-3,6,9-trioxaundecane
Synonym	More Synonyms

Description	Phthalamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₂₀N₄O₅
Molecular Weight	348.35400
Exact Mass	348.14300
PSA	114.82000
LogP	1.03336

2-(2-{2-[2-(2-Azido-ethoxy)-ethoxy]-ethoxy}-ethyl)-isoindole-1,3-dione