N-trifluoroacetyl (TFA)

Modify Date: 2024-01-05 12:06:16

N-trifluoroacetyl (TFA) Structure
N-trifluoroacetyl (TFA) structure
Common Name N-trifluoroacetyl (TFA)
CAS Number 133975-85-6 Molecular Weight 413.41500
Density N/A Boiling Point 433.696ºC at 760 mmHg
Molecular Formula C17H31F3N3O3P Melting Point N/A
MSDS USA Flash Point 216.092ºC

 Use of N-trifluoroacetyl (TFA)


N-trifluoroacetyl (TFA) protected aminolink C6 phosphoramidite for the synthesis of 5'-amino-modified oligonucleotides. TFA protection is smoothly removed during ammonia deprotection, and does not require any additional steps. If necessary, the resulting oligonucleotides can be purified by ion exchange chromatography, or gel electrophoresis.

 Names

Name 5'-amino-modifier-c 6-tfa cep
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 433.696ºC at 760 mmHg
Molecular Formula C17H31F3N3O3P
Molecular Weight 413.41500
Flash Point 216.092ºC
Exact Mass 413.20600
PSA 88.18000
LogP 4.90878
Vapour Pressure 0mmHg at 25°C
Storage condition 2-8℃

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

C6 TFA LINKER AMIDITE
trifluoroacetyl cyanoethyl phosphoramidite amino-linker