NCGC00229600

Modify Date: 2025-08-27 17:16:32

NCGC00229600 Structure
NCGC00229600 structure
Common Name NCGC00229600
CAS Number 1338824-20-6 Molecular Weight 479.57
Density N/A Boiling Point N/A
Molecular Formula C30H29N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NCGC00229600


NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].

 Names

Name NCGC00229600

 NCGC00229600 Biological Activity

Description NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].
Related Catalog
References

[1]. Neumann S, et al. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.

 Chemical & Physical Properties

Molecular Formula C30H29N3O3
Molecular Weight 479.57
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