Lucanthone-d4 hydrochloride

Modify Date: 2024-01-13 20:31:24

Lucanthone-d4 hydrochloride structure	Common Name	Lucanthone-d4 hydrochloride
	CAS Number	1329613-40-2	Molecular Weight	380.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₁D₄ClN₂OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lucanthone-d4 hydrochloride

Lucanthone-d4 hydrochloride is the deuterium labeled Lucanthone. Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1)[1][2].

Name	Lucanthone-d4 hydrochloride

Description	Lucanthone-d4 hydrochloride is the deuterium labeled Lucanthone. Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1)[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Chowdhury SM, et al. Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. Nanomedicine. 2015 Jan;11(1):109-18. [3]. Carew JS, et al. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem. 2011 Feb 25;286(8):6602-13.

Molecular Formula	C₂₀H₂₁D₄ClN₂OS
Molecular Weight	380.97

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Lucanthone-d4 hydrochloride
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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