Lucanthone-d4 hydrochloride

Modify Date: 2025-09-21 19:55:07

Lucanthone-d4 hydrochloride Structure
Lucanthone-d4 hydrochloride structure
Common Name Lucanthone-d4 hydrochloride
CAS Number 1329613-40-2 Molecular Weight 380.97
Density N/A Boiling Point N/A
Molecular Formula C20H21D4ClN2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lucanthone-d4 hydrochloride


Lucanthone-d4 hydrochloride is the deuterium labeled Lucanthone. Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1)[1][2].

 Names

Name Lucanthone-d4 hydrochloride

 Lucanthone-d4 hydrochloride Biological Activity

Description Lucanthone-d4 hydrochloride is the deuterium labeled Lucanthone. Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1)[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Chowdhury SM, et al. Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. Nanomedicine. 2015 Jan;11(1):109-18.

[3]. Carew JS, et al. Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem. 2011 Feb 25;286(8):6602-13.

 Chemical & Physical Properties

Molecular Formula C20H21D4ClN2OS
Molecular Weight 380.97
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