Glufosfamide

Modify Date: 2024-01-09 14:56:12

Glufosfamide Structure
Glufosfamide structure
Common Name Glufosfamide
CAS Number 132682-98-5 Molecular Weight 383.163
Density 1.6±0.1 g/cm3 Boiling Point 569.9±60.0 °C at 760 mmHg
Molecular Formula C10H21Cl2N2O7P Melting Point N/A
MSDS N/A Flash Point 298.5±32.9 °C

 Use of Glufosfamide


Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.

 Names

Name (2S,3R,4S,5S,6R)-2-bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol
Synonym More Synonyms

 Glufosfamide Biological Activity

Description Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.
Related Catalog
References

[1]. DollnerR, et al. Ex vivo responsiveness of head and neck squamous cell carcinoma to glufosfamide, a novelalkylating agent. Anticancer Res. 2004 Sep-Oct;24(5A):2947-51.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 569.9±60.0 °C at 760 mmHg
Molecular Formula C10H21Cl2N2O7P
Molecular Weight 383.163
Flash Point 298.5±32.9 °C
Exact Mass 382.046356
PSA 150.32000
LogP -1.07
Vapour Pressure 0.0±3.6 mmHg at 25°C
Index of Refraction 1.563

 Synthetic Route

~91%

Glufosfamide Structure

Glufosfamide

CAS#:132682-98-5

Literature: THRESHOLD PHARMACEUTICALS, INC. Patent: WO2008/11588 A2, 2008 ; Location in patent: Page/Page column 35 ;

 Synonyms

β-D-glucosyl-ifosfamide mustard
glc-IPM
β-D-Glucopyranose, 1-O-[bis[(2-chloroethyl)amino]phosphinyl]-
UNII-1W5N8SZD9A
b-D-Glucopyranose 1-(N,N'-Bis(2-chloroethyl)phosphorodiamidate)
Glucosylifostamide mustard
1-O-{Bis[(2-chloroethyl)amino]phosphoryl}-β-D-glucopyranose
Glufosfamide
Glucosyl-ifosfamide mustard
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Glufosfamide suppliers

Glufosfamide price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3