Citarinostat
Modify Date: 2025-08-25 19:29:59
Citarinostat structure
|
Common Name | Citarinostat | ||
|---|---|---|---|---|
| CAS Number | 1316215-12-9 | Molecular Weight | 467.948 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C24H26ClN5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CitarinostatCitarinostat is a HDAC6 specific inhibitor, with IC50 of 4 nM and 76 nM for HDAC6 and HDAC3, respectively.IC50 value: 4 nM (HDAC6), 76 nM (HDAC3)Target: HDACThe detailed information please refer to WO2015061684A1 and 2015054197A1. |
| Name | Citarinostat |
|---|---|
| Synonym | More Synonyms |
| Description | Citarinostat is a HDAC6 specific inhibitor, with IC50 of 4 nM and 76 nM for HDAC6 and HDAC3, respectively.IC50 value: 4 nM (HDAC6), 76 nM (HDAC3)Target: HDACThe detailed information please refer to WO2015061684A1 and 2015054197A1. |
|---|---|
| Related Catalog | |
| Target |
HDAC6:2.6 nM (IC50) HDAC1:35 nM (IC50) HDAC2:45 nM (IC50) HDAC3:46 nM (IC50) HDAC8:137 nM (IC50) HDAC7:7300 nM (IC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C24H26ClN5O3 |
| Molecular Weight | 467.948 |
| Exact Mass | 467.172424 |
| PSA | 107.45000 |
| LogP | 1.80 |
| Index of Refraction | 1.624 |
| InChIKey | VLIUIBXPEDFJRF-UHFFFAOYSA-N |
| SMILES | O=C(CCCCCCNC(=O)c1cnc(N(c2ccccc2)c2ccccc2Cl)nc1)NO |
| Storage condition | -20℃ |
| 2-[(2-Chlorophenyl)(phenyl)amino]-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide |
| Citarinostat |
| 2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxohepl)pyrimidine-5-carboxamide |
| 5-Pyrimidinecarboxamide, 2-[(2-chlorophenyl)phenylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]- |
| 2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide |
| ACY-241 |
| UNII:441P620G3P |
| ACY-241 Avi Tini |