Cornuside
Cornuside structure
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Common Name | Cornuside | ||
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| CAS Number | 131189-57-6 | Molecular Weight | 542.487 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 817.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H30O14 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 274.5±27.8 °C | |
Use of CornusideCornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases[1]. |
| Name | methyl (2R,3S,4R)-3-ethenyl-4-[2-(3,4,5-trihydroxybenzoyl)oxyethyl]-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate |
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| Synonym | More Synonyms |
| Description | Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases[1]. |
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| Related Catalog | |
| Target |
p38 MAP kinase NF-κB |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 817.6±65.0 °C at 760 mmHg |
| Molecular Formula | C24H30O14 |
| Molecular Weight | 542.487 |
| Flash Point | 274.5±27.8 °C |
| Exact Mass | 542.163574 |
| PSA | 221.90000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.648 |
| RIDADR | NONH for all modes of transport |
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| Precursor 0 | |
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| DownStream 2 | |
CAS#:149-91-7
CAS#:72463-81-1|
[Optimization of microwave-assisted extraction with RSM and HPLC determination for three iridoid glycosides in Cornus officinalis].
Zhong Yao Cai 34(7) , 1118-22, (2011) To establish a method of microwave-assisted extraction and high performance liquid chromatographic (HPLC) for simultaneous determination of three iridoid glycosides including loganin, sweroside and co... |
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Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography.
J. Pharm. Biomed. Anal. 48(1) , 194-7, (2008) A simple and rapid HPLC method was established for simultaneously determining six active components in Fructus Corni. The six components were separated on an Agilent Zorbax Extend C18 column (250 mmx4... |
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[Studies on the chemical constituents of Cornus officinalis Sieb et Zucc].
Yao Xue Xue Bao 27(11) , 845-8, (1992) A new bisiridoid glucoside named cornuside was isolated from the fruits of Cornus officinalis Sieb et Zucc. The structure of cornuside has been established by spectroscopic methods (IR, MS, 1HNMR, 13C... |
| Y0054 |
| N1926 |
| 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2R,3S,4R)- |
| Cornuside |
| Methyl (2R,3S,4R)-2-(β-D-glucopyranosyloxy)-4-{2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl}-3-vinyl-3,4-dihydro-2H-pyran-5-carboxylate |
- BioBioPha
- China
- Product Name: Cornuside
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Cornuside
- Price: ￥1888.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Cornuside
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Cornuside
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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