LY2979165

Modify Date: 2025-08-22 19:57:10

LY2979165 structure	Common Name	LY2979165
	CAS Number	1311385-32-6	Molecular Weight	390.415
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₂₂N₆O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LY2979165

LY2979165 is a mGlu2 agonist, which is a novel potent agent that is used as anti-depressants.IC50 Value:Target: mGluR

Name	(1R,2R,4S,5R,6R)-4-[[(2S)-2-aminopropanoyl]amino]-2-(1H-1,2,4-triazol-5-ylsulfanyl)bicyclo[3.1.0]hexane-4,6-dicarboxylic acid, azane, hydrate
Synonym	More Synonyms

Description	LY2979165 is a mGlu2 agonist, which is a novel potent agent that is used as anti-depressants.IC50 Value:Target: mGluR
Related Catalog	Research Areas >> Neurological Disease
References	[1]. http://clinicaltrials.gov/ct2/show/NCT01383967 [2]. Hanna L, Ceolin L, Lucas S, Monn J, Johnson B, Collingridge G, Bortolotto Z, Lodge D.Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist.Neuropharmacology. 2012 Mar 15. [3]. Ceolin L, Kantamneni S, Barker GR, Hanna L, Murray L, Warburton EC, Robinson ES, Monn JA, Fitzjohn SM, Collingridge GL, Bortolotto ZA, Lodge D.Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 recepto [4]. Liu W, Downing AC, Munsie LM, Chen P, Reed MR, Ruble CL, Landschulz KT, Kinon BJ, Nisenbaum LK.Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia.Pharmacogenomics J. 2012 Jun;12(3):246-54. [5]. Dominguez C, Prieto L, Valli MJ, Massey SM, Bures M, Wright RA, Johnson BG, Andis SL, Kingston A, Schoepp DD, Monn JA.Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate

Description

LY2979165 is a mGlu2 agonist, which is a novel potent agent that is used as anti-depressants.IC50 Value:Target: mGluR

Related Catalog

Research Areas >> Neurological Disease

References

[1]. http://clinicaltrials.gov/ct2/show/NCT01383967

[2]. Hanna L, Ceolin L, Lucas S, Monn J, Johnson B, Collingridge G, Bortolotto Z, Lodge D.Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist.Neuropharmacology. 2012 Mar 15.

[3]. Ceolin L, Kantamneni S, Barker GR, Hanna L, Murray L, Warburton EC, Robinson ES, Monn JA, Fitzjohn SM, Collingridge GL, Bortolotto ZA, Lodge D.Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 recepto

[4]. Liu W, Downing AC, Munsie LM, Chen P, Reed MR, Ruble CL, Landschulz KT, Kinon BJ, Nisenbaum LK.Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia.Pharmacogenomics J. 2012 Jun;12(3):246-54.

[5]. Dominguez C, Prieto L, Valli MJ, Massey SM, Bures M, Wright RA, Johnson BG, Andis SL, Kingston A, Schoepp DD, Monn JA.Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate

Molecular Formula	C₁₃H₂₂N₆O₆S
Molecular Weight	390.415
Exact Mass	390.132141
PSA	212.55000
LogP	0.70290
Storage condition	2-8℃

CS-0457

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-[[(2S)-2-amino-1-oxopropyl]amino]-4-(4H-1,2,4-triazol-3-ylthio)-, ammonium salt, (1R,2S,4R,5R,6R)-, hydrate (1:1)

mGlu2 agonist

(1R,2S,4R,5R,6R)-2-(L-Alanylamino)-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid ammoniate hydrate

LY2979165

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LY2979165
Price: Check
Purity: 98.0%
Delivery: 10 Day
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DC Chemicals Limited
China
Product Name: Ly2979165 Ammonium Salt
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: MGlu2 agonist
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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LY2979165

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.