Diatrizoate Meglumine

Modify Date: 2024-01-02 01:26:43

Diatrizoate Meglumine structure	Common Name	Diatrizoate Meglumine
	CAS Number	131-49-7	Molecular Weight	809.127
	Density	1.9465 (estimate)	Boiling Point	614.1ºC at 760mmHg
	Molecular Formula	C₁₈H₂₆I₃N₃O₉	Melting Point	189-193° (dec)
	MSDS	Chinese USA	Flash Point	N/A

Use of Diatrizoate Meglumine

Diatrizoate meglumine is the meglumine salt form of diatrizoate, an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.

Name	meglumine amidotrizoate
Synonym	More Synonyms

Density	1.9465 (estimate)
Boiling Point	614.1ºC at 760mmHg
Melting Point	189-193° (dec)
Molecular Formula	C₁₈H₂₆I₃N₃O₉
Molecular Weight	809.127
Exact Mass	808.880310
PSA	215.66000
LogP	1.44700
Vapour Pressure	6.19E-16mmHg at 25°C

Diatrizoate Meglumine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ4315000

CHEMICAL NAME :: Glucitol, 1-deoxy-1-(methylamino)-, 3,5-diacetamido-2,4,6-triiodobenzoate (salt), D-

CAS REGISTRY NUMBER :: 131-49-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C11-H9-I3-N2-O4.C7-H17-N-O5

MOLECULAR WEIGHT :: 809.17

WISWESSER LINE NOTATION :: 1VMR BI DI FI CVQ EMV1 &Q1YQYQYQYQ1M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 214 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in both tubules and glomeruli Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - urine volume decreased

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,392,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14565 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.126- 1976- Volume(issue)/page/year: 142,619,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.126- 1976- Volume(issue)/page/year: 142,619,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 26,921,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,32,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,595,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81430 No. of Facilities: 86 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1252 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81430 No. of Facilities: 1221 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 27048 (estimated) No. of Female Employees: 17626 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
RTECS	LZ4315000

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Megluminamidotrizoat

Diatrizoic Acid Methylglucamine

MFCD00069632

3,5-bis(acetylamino)-2,4,6-triiodobenzoic acid - (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:1)

Meglumin-diazetrizoat

1-deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate

3,5-diacetamido-2,4,6-triiodobenzoic acid,(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol

Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, compd. with D-glucitol, 1-deoxy-1-(methylamino)- (1:1)

Diatrizoate methylglucamine

Diatrizoate Meglumine

Hypaque meglumine

Renograffin

Meglumine amidotrizoate

Renografin M-76

Unipaque

Reno M-Dip

3,5-Diacetamido-2,4,6-triiodobenzoic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1)

Angiografin

D-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt)

Renurix

Renografin

Methylglucamine diatrizoate

acide 3,5-bis(acétylamino)-2,4,6-triiodobenzoïque - (2R,3R,4R,5S)-6-(méthylamino)hexane-1,2,3,4,5-pentol (1:1)

3,5-Bis(acetylamino)-2,4,6-triiodbenzolcarbonsäure--(2R,3R,4R,5S)-6-(methylamino)hexan-1,2,3,4,5-pentol(1:1)

N-Methyl-D-glucamine diatrizoate

Amidotrizoate meglumine

3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid compd. with 1-Deoxy-1-(methylamino)-D-glucitol (1:1)

Urografin 76

Urovist

EINECS 205-024-7

Cystografin

ioxeol

Meglumin-diatrizoat

meglumine diatriazoate

3,5-bis(acetylamino)-2,4,6-triiodobenzoic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1)

meglumine diatrizoate

Triombrast

Verografin

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Diatrizoate Meglumine
Price: ￥988.0/5g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Diatrizoate meglumine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Diatrizoate meglumine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Diatrizoate Meglumine

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