TROX-1

Modify Date: 2025-08-24 23:35:30

TROX-1 Structure
TROX-1 structure
Common Name TROX-1
CAS Number 1309601-26-0 Molecular Weight 434.85
Density N/A Boiling Point N/A
Molecular Formula C22H16ClFN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TROX-1


TROX-1 is an N-type calcium channel (CaV2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 can be used in chronic pain research[1].

 Names

Name 2H-Indol-2-one, 5-(3-chloro-4-fluorophenyl)-1,3-dihydro-3-methyl-3-(5-pyrimidinylmethyl)-1-(1H-1,2,4-triazol-5-yl)-, (3R)-

 TROX-1 Biological Activity

Description TROX-1 is an N-type calcium channel (CaV2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 can be used in chronic pain research[1].
Related Catalog
References

[1]. Swensen AM, et al. Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels. Mol Pharmacol. 2012 Mar;81(3):488-97.  

 Chemical & Physical Properties

Molecular Formula C22H16ClFN6O
Molecular Weight 434.85
InChIKey OABSWPUPIHULMQ-JOCHJYFZSA-N
SMILES CC1(Cc2cncnc2)C(=O)N(c2ncn[nH]2)c2ccc(-c3ccc(F)c(Cl)c3)cc21
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