RMM 46

Modify Date: 2025-10-17 18:19:53

RMM 46 Structure
RMM 46 structure
Common Name RMM 46
CAS Number 1307896-46-3 Molecular Weight 450.49
Density 1.277±0.06 g/cm3(Predicted) Boiling Point 725.5±60.0 °C(Predicted)
Molecular Formula C24H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RMM 46


RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].

 Names

Name 2-Cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl)acrylamide

 RMM 46 Biological Activity

Description RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].
Related Catalog
References

[1]. Miller RM, et al. Electrophilic fragment-based design of reversible covalent kinase inhibitors. J Am Chem Soc. 2013 Apr 10;135(14):5298-301.

 Chemical & Physical Properties

Density 1.277±0.06 g/cm3(Predicted)
Boiling Point 725.5±60.0 °C(Predicted)
Molecular Formula C24H26N4O5
Molecular Weight 450.49
InChIKey FCCMYBKAZCDQGX-LZYBPNLTSA-N
SMILES COc1cc(-c2n[nH]c3ccc(C=C(C#N)C(=O)NC(C)(C)CO)cc23)cc(OC)c1OC
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