1307896-46-3

1307896-46-3 structure

Name: RMM 46
Chemical Name: 2-Cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl)acrylamide
CAS Number: 1307896-46-3
Molecular Formula: C₂₄H₂₆N₄O₅
Molecular Weight: 450.49
Create Date: 2022-03-22 16:00:10
Modify Date: 2025-10-17 18:19:53
RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].

Name	2-Cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl)acrylamide

Description	RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAPKAPK2 (MK2) Research Areas >> Cancer
References	[1]. Miller RM, et al. Electrophilic fragment-based design of reversible covalent kinase inhibitors. J Am Chem Soc. 2013 Apr 10;135(14):5298-301.