Izilendustat hydrochloride

Modify Date: 2024-01-10 21:46:02

Izilendustat hydrochloride Structure
Izilendustat hydrochloride structure
Common Name Izilendustat hydrochloride
CAS Number 1303513-80-5 Molecular Weight 470.39
Density N/A Boiling Point N/A
Molecular Formula C22H29Cl2N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Izilendustat hydrochloride


Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].

 Names

Name Izilendustat hydrochloride

 Izilendustat hydrochloride Biological Activity

Description Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3].
Related Catalog
Target

prolyl hydroxylase[1]

References

[1]. Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1.

[2]. Robert Shalwitz, et al. Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. Patent WO2011057112A1.

[3]. Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.

 Chemical & Physical Properties

Molecular Formula C22H29Cl2N3O4
Molecular Weight 470.39