Name | Izilendustat hydrochloride |
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Description | Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)[1][2][3]. |
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Related Catalog | |
Target |
prolyl hydroxylase[1] |
References |
[1]. Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1. [3]. Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1. |
Molecular Formula | C22H29Cl2N3O4 |
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Molecular Weight | 470.39 |