Abafungin

Modify Date: 2024-01-08 09:51:07

Abafungin Structure
Abafungin structure
Common Name Abafungin
CAS Number 129639-79-8 Molecular Weight 378.491
Density 1.3±0.1 g/cm3 Boiling Point 533.6±52.0 °C at 760 mmHg
Molecular Formula C21H22N4OS Melting Point N/A
MSDS N/A Flash Point 276.5±30.7 °C

 Use of Abafungin


Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.

 Names

Name abafungin
Synonym More Synonyms

 Abafungin Biological Activity

Description Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.
Related Catalog
References

[1]. Borelli C, Schaller M, Niewerth M, et al. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-259.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 533.6±52.0 °C at 760 mmHg
Molecular Formula C21H22N4OS
Molecular Weight 378.491
Flash Point 276.5±30.7 °C
Exact Mass 378.151428
PSA 86.78000
LogP 5.94
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.671
Storage condition 2-8°C

 Synonyms

N-(4-(2-((2,4-Dimethylphenyl)oxy)phenyl)-1,3-thiazol-2-yl)-1,4,5,6-tetrahydro-2-pyrimidinamine
2-Pyrimidinamine, N-[4-[2-(2,4-dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-
bay w 6341
Hexahydro-2-[[4-[o-(2,4-xylyloxy)phenyl]-2-thiazolyl]imino]pyrimidine
BAY-W 6341
N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine
N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine
4-[2-(2,4-Dimethylphenoxy)phenyl]-N-(tetrahydropyrimidin-2(1H)-ylidene)-1,3-thiazol-2-amine
Abafungin
N-{4-[2-(2,4-Dimethylphenoxy)phenyl]-1,3-thiazol-2-yl}-1,4,5,6-tetrahydro-2-pyrimidinamine
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  • China
  • Product Name: Abafungin
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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