129639-79-8

129639-79-8 structure

Name: Abafungin
Chemical Name: abafungin
CAS Number: 129639-79-8
Molecular Formula: C₂₁H₂₂N₄OS
Molecular Weight: 378.491
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-09-06 14:55:23
Modify Date: 2024-01-08 09:51:07
Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.

Name	abafungin
Synonyms	N-(4-(2-((2,4-Dimethylphenyl)oxy)phenyl)-1,3-thiazol-2-yl)-1,4,5,6-tetrahydro-2-pyrimidinamine 2-Pyrimidinamine, N-[4-[2-(2,4-dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro- bay w 6341 Hexahydro-2-[[4-[o-(2,4-xylyloxy)phenyl]-2-thiazolyl]imino]pyrimidine BAY-W 6341 N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine 4-[2-(2,4-Dimethylphenoxy)phenyl]-N-(tetrahydropyrimidin-2(1H)-ylidene)-1,3-thiazol-2-amine Abafungin N-{4-[2-(2,4-Dimethylphenoxy)phenyl]-1,3-thiazol-2-yl}-1,4,5,6-tetrahydro-2-pyrimidinamine

Description	Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Borelli C, Schaller M, Niewerth M, et al. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-259.