2,3-Diphosphoglyceric acid pentasodium

Modify Date: 2025-08-27 16:53:11

2,3-Diphosphoglyceric acid pentasodium Structure
2,3-Diphosphoglyceric acid pentasodium structure
Common Name 2,3-Diphosphoglyceric acid pentasodium
CAS Number 1287756-01-7 Molecular Weight 375.95
Density N/A Boiling Point N/A
Molecular Formula C3H3Na5O10P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2,3-Diphosphoglyceric acid pentasodium


2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2].

 Names

Name Glycerate 2,3-Diphosphate SodiuM

 2,3-Diphosphoglyceric acid pentasodium Biological Activity

Description 2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2].
Related Catalog
References

[1]. Shakil H. Merchant MD, et al. 24 - Molecular Diagnosis in Hematopathology. Hematopathology (Second Edition).2012, 679-726.

[2]. Płoszczyca K, et al. Red Blood Cell 2,3-Diphosphoglycerate Decreases in Response to a 30 km Time Trial Under Hypoxia in Cyclists. Front Physiol. 2021 Jun 15;12:670977.  

 Chemical & Physical Properties

Molecular Formula C3H3Na5O10P2
Molecular Weight 375.95
InChIKey KPRMRMXBVAUXKZ-UHFFFAOYSA-I
SMILES O=C([O-])C(COP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+]
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