Gingerenone A

Modify Date: 2024-01-02 21:30:18

Gingerenone A Structure
Gingerenone A structure
Common Name Gingerenone A
CAS Number 128700-97-0 Molecular Weight 356.41
Density 1.183g/cm3 Boiling Point 571.3ºC at 760mmHg
Molecular Formula C21H24O5 Melting Point N/A
MSDS N/A Flash Point 200.3ºC

 Use of Gingerenone A


Gingerenone A is a Nrf2-Gpx4 activator with anti-breast-cancer properties. Gingerenone A results a delayed G2/M in cancer cells, following oxidative stress and senescence responses. Gingerenone A also alleviates ferroptosis in secondary liver injury (SLI) in dextran sodium sulfate (DSS)-induced colitis mice. Gingerenone A can be isolated from Zingiber officinale[1][2].

 Names

Name (E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one
Synonym More Synonyms

 Gingerenone A Biological Activity

Description Gingerenone A is a Nrf2-Gpx4 activator with anti-breast-cancer properties. Gingerenone A results a delayed G2/M in cancer cells, following oxidative stress and senescence responses. Gingerenone A also alleviates ferroptosis in secondary liver injury (SLI) in dextran sodium sulfate (DSS)-induced colitis mice. Gingerenone A can be isolated from Zingiber officinale[1][2].
Related Catalog
Target

Nrf2-Gpx4[1]

References

[1]. Yu TJ, et al. Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells. Antioxidants (Basel). 2022 Mar 19;11(3):587.  

[2]. Chen Y, et al. Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway. J Agric Food Chem. 2022 Oct 5;70(39):12525-12534.  

 Chemical & Physical Properties

Density 1.183g/cm3
Boiling Point 571.3ºC at 760mmHg
Molecular Formula C21H24O5
Molecular Weight 356.41
Flash Point 200.3ºC
Exact Mass 356.16200
PSA 75.99000
LogP 3.80570
Vapour Pressure 1.19E-13mmHg at 25°C
Index of Refraction 1.583
Storage condition 2-8 °C

 Synonyms

(E)-gingerenone A
(E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-4-hepten-3-one
Y7369
gingerenone-A
1,7-bis(4-hydroxy-3-methoxyphenyl)-hept-4-en-3-one
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Gingerenone A
  • Price: ¥3400.0/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng



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Price: ¥620/5 mg

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