PLpro/RBD-IN-1

Modify Date: 2024-01-13 05:53:36

Use of PLpro/RBD-IN-1

PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1].

Name	PLpro/RBD-IN-1

Description	PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 7.197 μM (SARS-CoV-2 PLpro) and 8.673 μM (spike protein RBD)[1]
References	[1]. Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272.

Molecular Formula	C₁₃H₁₀N₄O
Molecular Weight	238.24