PLpro/RBD-IN-1

Names

[ CAS No. ]:
1282451-83-5

[ Name ]:
PLpro/RBD-IN-1

Biological Activity

[Description]:

PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

IC50: 7.197 μM (SARS-CoV-2 PLpro) and 8.673 μM (spike protein RBD)[1]


[References]

[1]. Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H10N4O

[ Molecular Weight ]:
238.24

Related Compounds