Odoroside A

Modify Date: 2024-01-11 12:15:43

Odoroside A Structure
Odoroside A structure
Common Name Odoroside A
CAS Number 12738-19-1 Molecular Weight 518.68200
Density 1.22g/cm3 Boiling Point 662.5ºC at 760mmHg
Molecular Formula C30H46O7 Melting Point N/A
MSDS N/A Flash Point 211.8ºC

 Use of Odoroside A


Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death[1].

 Names

Name 3-[(2,6-Dideoxy-3-O-methylhexopyranosyl)oxy]-14-hydroxycard-20(22 )-enolide
Synonym More Synonyms

 Odoroside A Biological Activity

Description Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death[1].
Related Catalog
References

[1]. Chen YY, et al. Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway. Proteomics. 2019;19(15):e1900092.

 Chemical & Physical Properties

Density 1.22g/cm3
Boiling Point 662.5ºC at 760mmHg
Molecular Formula C30H46O7
Molecular Weight 518.68200
Flash Point 211.8ºC
Exact Mass 518.32400
PSA 94.45000
LogP 4.13940

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RI3400000
CHEMICAL NAME :
Odoroside A
CAS REGISTRY NUMBER :
12738-19-1
LAST UPDATED :
199009
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C30-H46-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
186 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,420,1951 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,192,1963

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

o-Dopaquinone
odoroside-A
L-dopaquinone
Dopa O-Quinone
DOPA quinone
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