Odoroside A

Names

[ Name ]:
Odoroside A

[Synonym ]:
o-Dopaquinone
odoroside-A
L-dopaquinone
Dopa O-Quinone
DOPA quinone

Biological Activity

[Description]:

Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Chen YY, et al. Proteomic Analysis Reveals that Odoroside A Triggers G2/M Arrest and Apoptosis in Colorectal Carcinoma Through ROS-p53 Pathway. Proteomics. 2019;19(15):e1900092.

Chemical & Physical Properties

[ Density]:
1.22g/cm3

[ Boiling Point ]:
662.5ºC at 760mmHg

[ Molecular Formula ]:
C₃₀H₄₆O₇

[ Molecular Weight ]:
518.68200

[ Flash Point ]:
211.8ºC

[ Exact Mass ]:
518.32400

[ PSA ]:
94.45000

[ LogP ]:
4.13940

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RI3400000

CHEMICAL NAME :: Odoroside A

CAS REGISTRY NUMBER :: 12738-19-1

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C30-H46-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 186 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,420,1951 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,192,1963

Precursor & DownStream

Precursor

DownStream

Related Compounds

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