(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate

Modify Date: 2025-08-26 21:49:49

(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate structure	Common Name	(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate
	CAS Number	1268163-15-0	Molecular Weight	331.36800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₇N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate

TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. TL8-506 can be used for the research of tuberculosis and autoimmune diseases[1].

Name	(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate

Description	TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. TL8-506 can be used for the research of tuberculosis and autoimmune diseases[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
References	[1]. Jun Tang, et al. Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection. Front Immunol. 2018 Jan 24;8:1972.

Molecular Formula	C₂₀H₁₇N₃O₂
Molecular Weight	331.36800
Exact Mass	331.13200
PSA	88.47000
LogP	3.70008
InChIKey	YHRYTTWRVKXODS-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=Cc2ccc(-c3cccc(C#N)c3)cc2N=C(N)C1

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