(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate

Names

[ Name ]:
(1E,4E)-ethyl 2-amino-8-(3-cyanophenyl)-3H-benzo[b]azepine-4-carboxylate

Biological Activity

[Description]:

TL8-506 is a specific TLR8 agonist with an EC50 of 30 nM. TL8-506 can be used for the research of tuberculosis and autoimmune diseases[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Inflammation/Immunology

[References]

[1]. Jun Tang, et al. Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection. Front Immunol. 2018 Jan 24;8:1972.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₇N₃O₂

[ Molecular Weight ]:
331.36800

[ Exact Mass ]:
331.13200

[ PSA ]:
88.47000

[ LogP ]:
3.70008

Related Compounds

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