endo-BCN-PEG2-NH2

Modify Date: 2024-01-06 11:51:58

endo-BCN-PEG2-NH2 Structure
endo-BCN-PEG2-NH2 structure
Common Name endo-BCN-PEG2-NH2
CAS Number 1263166-93-3 Molecular Weight 324.41500
Density N/A Boiling Point N/A
Molecular Formula C17H28N2O4 Melting Point N/A
MSDS USA Flash Point N/A

 Use of endo-BCN-PEG2-NH2


endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Synonym More Synonyms

 endo-BCN-PEG2-NH2 Biological Activity

Description endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H28N2O4
Molecular Weight 324.41500
Exact Mass 324.20500
PSA 82.81000
LogP 2.23530
Storage condition -20°C

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

MFCD19705418
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