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1263166-93-3

1263166-93-3 structure
1263166-93-3 structure
  • Name: endo-BCN-PEG2-NH2
  • Chemical Name: N-[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
  • CAS Number: 1263166-93-3
  • Molecular Formula: C17H28N2O4
  • Molecular Weight: 324.41500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-03-10 03:38:15
  • Modify Date: 2024-01-06 11:51:58
  • endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-[(1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Synonyms MFCD19705418
Description endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H28N2O4
Molecular Weight 324.41500
Exact Mass 324.20500
PSA 82.81000
LogP 2.23530
Storage condition -20°C
RIDADR NONH for all modes of transport