L-(+)-2-AMINO-6-PHOSPHONOHEXANOIC ACID
L-(+)-2-AMINO-6-PHOSPHONOHEXANOIC ACID structure
|
Common Name | L-(+)-2-AMINO-6-PHOSPHONOHEXANOIC ACID | ||
|---|---|---|---|---|
| CAS Number | 126253-57-4 | Molecular Weight | 211.153 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 479.3±55.0 °C at 760 mmHg | |
| Molecular Formula | C6H14NO5P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 243.6±31.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | L-AP6 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 479.3±55.0 °C at 760 mmHg |
| Molecular Formula | C6H14NO5P |
| Molecular Weight | 211.153 |
| Flash Point | 243.6±31.5 °C |
| Exact Mass | 211.060959 |
| LogP | -2.39 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.529 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | NONH for all modes of transport |
|
The lathyrus toxin, beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (ODAP), and homocysteic acid sensitize CA1 pyramidal neurons to cystine and L-2-amino-6-phosphonohexanoic acid.
Toxicol. Appl. Pharmacol. 219 , 1-9, (2007) A brief exposure of hippocampal slices to L-quisqualic acid (QUIS) sensitizes CA1 pyramidal neurons 30- to 250-fold to depolarization by certain excitatory amino acids analogues, e.g., L-2-amino-6-pho... |
|
|
L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization.
Neuroscience 106 , 287-301, (2001) A brief exposure of hippocampal slices to L-quisqualic acid sensitizes CA1 pyramidal neurons 30-250-fold to depolarization by two classes of excitatory amino acid analogues: (1) those whose depolarizi... |
|
|
Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.
Brain Res. 649 , 203-207, (1994) Brief exposure of rat hippocampal slices to quisqualic acid (QUIS) sensitizes neurons to depolarization by the alpha-amino-omega-phosphonate excitatory amino acid (EAA) analogues AP4, AP5 and AP6. The... |
| L-Norleucine, 6-phosphono- |
| L-AP6 |
| DL-Norleucine, 6-phosphono- |
| L-(+)-2-Amino-6-phosphonohexanoic acid |
| 6-Phosphono-L-norleucine |
| MFCD00144531 |