RO495

Modify Date: 2025-08-25 18:58:48

RO495 Structure
RO495 structure
Common Name RO495
CAS Number 1258296-60-4 Molecular Weight 389.24
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H14Cl2N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RO495


RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1].

 Names

Name N-{2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl}-2,6-dichlorobenzamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C17H14Cl2N6O
Molecular Weight 389.24
Exact Mass 388.060608
LogP 4.36
Index of Refraction 1.739
InChIKey LNGDQKGREFSTHB-UHFFFAOYSA-N
SMILES Cc1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)nc(N)n1
Storage condition -20°C

 Synonyms

Benzamide, N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro-
N-{2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl}-2,6-dichlorobenzamide
RO495
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