1258296-60-4

1258296-60-4 structure

Name: RO495
Chemical Name: N-{2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl}-2,6-dichlorobenzamide
CAS Number: 1258296-60-4
Molecular Formula: C₁₇H₁₄Cl₂N₆O
Molecular Weight: 389.24
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2018-04-17 15:03:02
Modify Date: 2025-08-25 18:58:48
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1].

Name	N-{2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl}-2,6-dichlorobenzamide
Synonyms	Benzamide, N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro- N-{2-[(2-Amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl}-2,6-dichlorobenzamide RO495

Description	RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	TYK2
References	[1]. Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640.