Compound 7

Modify Date: 2024-01-09 17:45:35

Compound 7 structure	Common Name	Compound 7
	CAS Number	1252003-13-6	Molecular Weight	335.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₁N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Compound 7

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity[1].

Name	HDAC-IN-4

Description	HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
Target	pIC50: 7.2 (HDAC6), and 6.8 (HDAC10)[1]
In Vitro	HDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC50s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET assay, respectively[1]. HDAC-IN-4 is more potent against HDAC6 than Tubastatin A, suggests that HDAC-IN-4 may be a better HDAC6 probe than Tubastatin A[1].
References	[1]. Géraldy M, et al. Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated. J Med Chem. 2019 May 9;62(9):4426-4443.

Molecular Formula	C₂₀H₂₁N₃O₂
Molecular Weight	335.40

DC Chemicals Limited
China
Product Name: Compound 7
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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