ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate
Modify Date: 2024-01-04 20:06:07
ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate structure
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Common Name | ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate | ||
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| CAS Number | 124811-87-6 | Molecular Weight | 261.27300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H15NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylateAnticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo[1]. |
| Name | ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate |
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| Synonym | More Synonyms |
| Description | Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo[1]. |
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| Related Catalog | |
| In Vitro | Anticancer agent 73 (compound CIB-3b) (10 μM; 6 hours) increases the expression of E-cadherin and decreases the protein expression levels of fibronectin, N-cadherin, and vimentin in SK-HEP-1 cells; inhibits the proliferation and migration of SK-HEP-1, HCCLM3 and MHCC97L cells by inhibiting miRNA biogenesis[1]. |
| In Vivo | Anticancer agent 73 (10, 25 and 50 mg/kg; IV, every 2 days for 4 weeks) attenuates the proliferation and migration of SK-HEP-1 and SK-HEP-1 implanted in SCID mice[1] |
| References |
| Molecular Formula | C14H15NO4 |
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| Molecular Weight | 261.27300 |
| Exact Mass | 261.10000 |
| PSA | 61.56000 |
| LogP | 2.83530 |
| 2-(4-methoxy-phenyl)-5-methyl-oxazole-4-carboxylic acid ethyl ester |
| ethyl 5-methyl-2-(4-methoxy)phenyl-4-oxazolecarboxylate |
| 2-(4-Methoxyphenyl)-4-carbethoxy-5-methyloxazole |