5-Fluoromethylornithine dihydrochloride

Modify Date: 2024-01-05 12:26:07

5-Fluoromethylornithine dihydrochloride Structure
5-Fluoromethylornithine dihydrochloride structure
Common Name 5-Fluoromethylornithine dihydrochloride
CAS Number 124796-41-4 Molecular Weight 237.10
Density N/A Boiling Point N/A
Molecular Formula C6H15Cl2FN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Fluoromethylornithine dihydrochloride


5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina[1][2].

 Names

Name 5-Fluoromethylornithine dihydrochloride

 5-Fluoromethylornithine dihydrochloride Biological Activity

Description 5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina[1][2].
Related Catalog
References

[1]. Daune G, et al. 5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase. Biochem J. 1988 Jul 15;253(2):481-8.  

[2]. Nakauchi T, et al. Prevention of ornithine cytotoxicity by nonpolar side chain amino acids in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):5023-8.  

 Chemical & Physical Properties

Molecular Formula C6H15Cl2FN2O2
Molecular Weight 237.10
InChIKey ZOZPMKYVFZNAHT-UHFFFAOYSA-N
SMILES Cl.Cl.NC(CF)CCC(N)C(=O)O
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