5-Fluoromethylornithine dihydrochloride

Names

[ CAS No. ]:
124796-41-4

[ Name ]:
5-Fluoromethylornithine dihydrochloride

Biological Activity

[Description]:

5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Daune G, et al. 5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase. Biochem J. 1988 Jul 15;253(2):481-8.  

[2]. Nakauchi T, et al. Prevention of ornithine cytotoxicity by nonpolar side chain amino acids in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):5023-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C6H15Cl2FN2O2

[ Molecular Weight ]:
237.10

Related Compounds

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