Sotalol D6 hydrochloride

Modify Date: 2025-08-26 22:32:07

Sotalol D6 hydrochloride Structure
Sotalol D6 hydrochloride structure
Common Name Sotalol D6 hydrochloride
CAS Number 1246820-85-8 Molecular Weight 314.862
Density N/A Boiling Point N/A
Molecular Formula C12H15D6ClN2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sotalol D6 hydrochloride


Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitive β-adrenergic receptor antagonist that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels[1][2].

 Names

Name N-(4-{1-Hydroxy-2-[(1,1,1,3,3,3-2H6)-2-propanylamino]ethyl}phenyl)methanesulfonamide hydrochloride (1:1)
Synonym More Synonyms

 Sotalol D6 hydrochloride Biological Activity

Description Sotalol D6 hydrochloride is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is a non-selective competitive β-adrenergic receptor antagonist that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels[1][2].
Related Catalog
Target

β-adrenergic receptor[1]; Potassium channels[1]

References

[1]. Antonaccio, M.J. and A. Gomoll, Pharmacologic basis of the antiarrhythmic and hemodynamic effects of sotalol. Am J Cardiol, 1993. 72(4): p. 27A-37A.

[2]. Bertrix, L., et al., Protection against ventricular and atrial fibrillation by sotalol. Cardiovasc Res, 1986. 20(5): p. 358-63

 Chemical & Physical Properties

Molecular Formula C12H15D6ClN2O3S
Molecular Weight 314.862
Exact Mass 314.133789

 Synonyms

Methanesulfonamide, N-[4-[1-hydroxy-2-[[1-(methyl-d3)ethyl-2,2,2-d3]amino]ethyl]phenyl]-, hydrochloride (1:1)
N-(4-{1-Hydroxy-2-[(1,1,1,3,3,3-2H6)-2-propanylamino]ethyl}phenyl)methanesulfonamide hydrochloride (1:1)
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