Fenspiride-d5 hydrochloride

Modify Date: 2025-08-26 11:04:33

Fenspiride-d5 hydrochloride structure	Common Name	Fenspiride-d5 hydrochloride
	CAS Number	1246815-28-0	Molecular Weight	301.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₆D₅ClN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fenspiride-d5 hydrochloride

Fenspiride-d5 hydrochloride is the deuterium labeled Fenspiride hydrochloride. Fenspiride hydrochloride is an α adrenergic and H1 histamine receptor antagonist[1][2].

Name	Fenspiride-d5 hydrochloride

Description	Fenspiride-d5 hydrochloride is the deuterium labeled Fenspiride hydrochloride. Fenspiride hydrochloride is an α adrenergic and H1 histamine receptor antagonist[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Lebedenko AA, Mal'tsev SV..[The efficacy of application of fenspiride (erespal) for the treatment of exacerbation of bronchial asthma in children.]Vestn Otorinolaringol. 2011;(4):66-67. [3]. Khawaja AM, Liu YC, Rogers DF. et al.Effect of fenspiride, a non-steroidal antiinflammatory agent, on neurogenic mucus secretion in ferret trachea in vitro. Pulm Pharmacol Ther. 1999;12(6):363-8. [4]. Zielnik-Jurkiewicz B, Jurkiewicz D. et al. Usefulness of fenspiride in the treatment of acute otitis media in children. Pol Merkur Lekarski. 2005 Jun;18(108):624-8. [5]. Bee D, Laude EA, Emery CJ, Howard P. Effect of fenspiride on pulmonary function in the rat and guinea pig. Clin Sci (Lond). 1995 Mar;88(3):325-30. [6]. Fenspiride

Molecular Formula	C₁₅H₁₆D₅ClN₂O₂
Molecular Weight	301.82

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